Unknown

Dataset Information

0

Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets.


ABSTRACT: There is an urgent need for new diagnosis and treatment options for the bacterial pathogen Staphylococcus aureus. This review will summarize data on ten recently discovered biofilm-associated serine hydrolases called fluorophosphonate-binding hydrolases (FphA-J). Based on the summarized findings, many of these proteins represent intriguing new targets for probe and drug development.

SUBMITTER: Fellner M 

PROVIDER: S-EPMC8957240 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

altmetric image

Publications

Newly discovered <i>Staphylococcus aureus</i> serine hydrolase probe and drug targets.

Fellner Matthias M  

ADMET & DMPK 20211028 2


There is an urgent need for new diagnosis and treatment options for the bacterial pathogen Staphylococcus aureus. This review will summarize data on ten recently discovered biofilm-associated serine hydrolases called fluorophosphonate-binding hydrolases (FphA-J). Based on the summarized findings, many of these proteins represent intriguing new targets for probe and drug development. ...[more]

Similar Datasets

| S-EPMC10870370 | biostudies-literature
| S-EPMC5258850 | biostudies-literature
| S-EPMC3372466 | biostudies-literature
| S-EPMC97868 | biostudies-literature
| S-EPMC2876493 | biostudies-literature
| S-EPMC98051 | biostudies-literature
2010-04-01 | GSE20973 | GEO
| S-EPMC4246989 | biostudies-literature
| S-EPMC11428220 | biostudies-literature
| S-EPMC3949172 | biostudies-literature