Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets.

ABSTRACT: There is an urgent need for new diagnosis and treatment options for the bacterial pathogen Staphylococcus aureus. This review will summarize data on ten recently discovered biofilm-associated serine hydrolases called fluorophosphonate-binding hydrolases (FphA-J). Based on the summarized findings, many of these proteins represent intriguing new targets for probe and drug development.

SUBMITTER: Fellner M 

PROVIDER: S-EPMC8957240 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature