Ontology highlight
ABSTRACT:
SUBMITTER: Siddiqui JA
PROVIDER: S-EPMC8957514 | biostudies-literature | 2022 Apr
REPOSITORIES: biostudies-literature
Siddiqui Jawed Akhtar JA Pothuraju Ramesh R Khan Parvez P Sharma Gunjan G Muniyan Sakthivel S Seshacharyulu Parthasarathy P Jain Maneesh M Nasser Mohd Wasim MW Batra Surinder Kumar SK
Cytokine & growth factor reviews 20211117
Growth differentiation factor 15 or macrophage inhibitory cytokine-1 (GDF15/MIC-1) is a divergent member of the transforming growth factor β superfamily and has a diverse pathophysiological roles in cancers, cardiometabolic disorders, and other diseases. GDF15 controls hematopoietic growth, energy homeostasis, adipose tissue metabolism, body growth, bone remodeling, and response to stress signals. The role of GDF15 in cancer development and progression is complicated and depends on the specific ...[more]