Postdischarge prophylactic antibiotics following mastectomy with and without breast reconstruction.

ABSTRACT:

Background

Prophylactic antibiotics are commonly prescribed at discharge for mastectomy, despite guidelines recommending against this practice. We investigated factors associated with postdischarge prophylactic antibiotic use after mastectomy with and without immediate reconstruction and the impact on surgical-site infection (SSI).

Study design

We studied a cohort of women aged 18-64 years undergoing mastectomy between January 1, 2010, and June 30, 2015, using the MarketScan commercial database. Patients with nonsurgical perioperative infections were excluded. Postdischarge oral antibiotics were identified from outpatient drug claims. SSI was defined using International Classification of Diseases, Ninth Edition, Clinical Modification (ICD-9-CM) diagnosis codes. Genera

SUBMITTER: Warren DK 

PROVIDER: S-EPMC8957624 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature