Effect of Serum Phosphate on the Prognosis of Septic Patients: A Retrospective Study Based on MIMIC-IV Database.

ABSTRACT:

Objective

To assess the effect of serum inorganic phosphate (Pi) on the prognosis of patients with sepsis.

Methods

A retrospective analysis of patients with sepsis selected from the Medical Information Mart for Intensive Care (MIMIC)-IV database was performed. Sepsis was diagnosed according to the Third International Consensus Definition for sepsis and septic shock (Sepsis-3). The time-weighted values of the serum Pi measurements within the first 24 h of sepsis were analyzed. The association between serum Pi and in-hospital mortality was evaluated with a generalized linear model (log-binomial model).

Results

The analysis of 11,658 patients from six intensive care units (ICUs) showed a nearly linear correlation between serum Pi and in-hospital mortality in all patients

SUBMITTER: Li Z 

PROVIDER: S-EPMC8957859 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature