Alloyed nanostructures integrated metal-phenolic nanoplatform for synergistic wound disinfection and revascularization.

ABSTRACT: New materials for combating bacteria-caused infection and promoting the formation of microvascular networks during wound healing are of vital importance. Although antibiotics can be used to prevent infection, treatments that can disinfect and accelerate wound healing are scarce. Herein, we engineer a coating that is both highly compatible with current wound dressing substrates and capable of simultaneously disinfecting and revascularizing wounds using a metal-phenolic nanoplatform containing an alloyed nanostructured architecture (Ag@Cu-MPN_NC). The alloyed nanostructure is formed by the spontaneous co-reduction and catalytic disproportionation reaction of multiple metal ions on a foundation metal-phenolic supramolecular layer. This synergistic presence of metals greatly improves

SUBMITTER: Xie Y 

PROVIDER: S-EPMC8958420 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature