Low-Valent Tungsten Catalysis Enables Site-Selective Isomerization-Hydroboration of Unactivated Alkenes.

ABSTRACT: A tungsten-catalyzed hydroboration of unactivated alkenes at distal C(sp³)-H bonds aided by native directing groups is described herein. The method is characterized by its simplicity, exquisite regio- and chemoselectivity, and wide substrate scope, offering a complementary site-selectivity pattern to other metal-catalyzed borylation reactions and chain-walking protocols.

SUBMITTER: Jankins TC 

PROVIDER: S-EPMC8958473 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature