Sociodemographic disparities in gastric cancer and the gastric precancerous cascade: A population-based study.

ABSTRACT:

Background

Gastric carcinogenesis is a multistep process initiating with chronic gastritis and progressing through atrophy, intestinal metaplasia, and dysplasia to carcinoma. This study aims to comprehensively investigate sociodemographic disparities in each stage of gastric carcinogenesis and estimate to what extent the inequalities could be ascribed to risk factors of gastric cancer (GC).

Methods

We used the baseline data from a community-based study in China's high-risk areas, totalling 27094 participants. Gastric mucosa status was ascertained by endoscopy and biopsies. An overall socioeconomic status (SES) variable was generated by latent class analysis. We calculated relative risks (RRs) and 95% confidence intervals (CIs) using modified Poisson regression to assess asso

SUBMITTER: Sun D 

PROVIDER: S-EPMC8958536 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature