Efficacy and safety of direct oral anticoagulants with and without Aspirin: A systematic review and Meta-analysis.

ABSTRACT:

Background

Various anticoagulant therapies are prescribed to patients under physicians' discretion and recently Direct Oral Anticoagulants(DOAC) have been under trials to evaluate their safety and efficacy. In addition to this, the regimen of DOACs and Aspirin is of keen interest as researchers continue to find an optimal regimen to treat blood clots in patients. This study is a systematic review and meta-analysis of randomized controlled trials and observational studies that asses the safety and efficacy of DOAC with and without Aspirin.

Methods

We queried MEDLINE and Cochrane CENTRAL from their inception to April 2021, for published and randomized controlled trials and observational studies in any language that compared dual (DOAC + ASA) therapy or mono (DOAC alone)

SUBMITTER: Almas T 

PROVIDER: S-EPMC8958538 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature