Ontology highlight
ABSTRACT:
SUBMITTER: Jahnmatz P
PROVIDER: S-EPMC8959630 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Jahnmatz Peter P Nyabundi Diana D Sundling Christopher C Widman Linnea L Mwacharo Jedidah J Musyoki Jennifer J Otieno Edward E Ahlborg Niklas N Bejon Philip P Ndungu Francis M FM Färnert Anna A
Frontiers in immunology 20220309
Identifying the mechanism of naturally acquired immunity against <i>Plasmodium falciparum</i> malaria could contribute to the design of effective malaria vaccines. Using a recently developed multiplexed FluoroSpot assay, we assessed cross-sectional pre-existing memory B-cells (MBCs) and antibody responses against six well known <i>P. falciparum</i> antigens (MSP-1<sub>19</sub>, MSP-2 (3D7), MSP-2 (FC27), MSP-3, AMA-1 and CSP) and measured their associations with previous infections and time to c ...[more]