The Multivariate Effect of Ketamine on PTSD: Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Post-traumatic stress disorder (PTSD) is a serious stress-related disorder caused by traumatic experiences. However, identifying a key therapy that can be used for PTSD treatment remains difficult. Ketamine, a well-known dissociative anesthetic, is considered safe to be used in anesthesia, pain management, and antidepressant actions since 1970. At present, it is still controversial whether PTSD can be treated with ketamine. The authors performed a meta-analysis to determine whether the use of perioperative ketamine lowers the incidence of PTSD.

Methods

Cochrane Central Register of Controlled Trials, Embase, PubMed, and Web of Science were searched to examine the use of ketamine for the treatment of PTSD among soldiers with combating experience. Studies were includ

SUBMITTER: Du R 

PROVIDER: S-EPMC8959757 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature