A Multimodal Score Accurately Classifies Fontan Failure and Late Mortality in Adult Fontan Patients.

ABSTRACT:

Objectives

Despite the outstanding success of the Fontan operation, it is a palliative procedure and a substantial number of patients experience late failure of the Fontan circulation. Clinical presentation and hemodynamic phenotypes of Fontan failure are considerably variable. While various parameters have been identified as risk factors for late Fontan failure, a feasible score to classify Fontan failure and possibly allow timely risk stratification is lacking. Here, we explored the possibility of developing a score based on hemodynamic, clinical and laboratory parameters to classify Fontan failure and mortality.

Methods

We performed a retrospective study in our cohort of adult Fontan patients from two institutions [n = 198, median follow-up after Fontan 20.3 (IQR 1

SUBMITTER: Kramer P 

PROVIDER: S-EPMC8960137 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature