A Prediction Equation to Estimate Vascular Endothelial Function in Different Body Mass Index Populations.

ABSTRACT:

Objective

Vascular endothelial dysfunction is considered an early predictor of endothelial injury and the initiating factor of atherosclerosis (AS). Brachial artery flow-mediated dilation (FMD) can detect endothelial injury early and provide important prognostic information beyond traditional cardiovascular (CV) risk factors. This study aimed to find the influencing factors of FMD and develop a simple prediction model in populations with different body mass indices (BMIs).

Methods

In total, 420 volunteers with different BMIs were recruited in our study. Subjects were randomly assigned to the derivation and validation cohorts (the ratio of the two was 1:2) with simple random sampling. The former was used for influencing factors searching and model construction of FMD and the

SUBMITTER: Li X 

PROVIDER: S-EPMC8960173 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature