Ontology highlight
ABSTRACT:
SUBMITTER: Li T
PROVIDER: S-EPMC8960194 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Li Tianye T Hao Zhenzhen Z Tang Zihan Z Li Chunting C Cheng Linglin L Wang Tao T Zhu Xiaojin X He Yunhao Y Huang Yongye Y Wang Bing B
Frontiers in oncology 20220310
B-cell receptor-associated protein 31 (BAP31) has been shown to overexpress in a wide range type of cancers. The present study aims to investigate the role of BAP31 on migration in lung cancer. Results showed that the migration of BAP31 knockdown cells was weaken than the control cells. Applying TGFβ to treat BAP31 knockdown cells could reduce cell migration. The enhancement on proliferation by TGFβ treatment was downregulated after BAP31 knockdown. The cell death and G0/G1 phase arrest was incr ...[more]