Age-related neural dedifferentiation for individual stimuli: an across-participant pattern similarity analysis.

ABSTRACT: Age-related neural dedifferentiation - reductions in the regional specificity and precision of neural representations - is proposed to compromise the ability of older adults to form sufficiently distinct neural representations to support episodic memory encoding. The computational model that spurred investigations of age-related neural dedifferentiation initially characterized this phenomenon as a reduction in the specificity of neural patterns for individual items or stimuli. Most investigations have focused on reductions in neural differentiation for patterns of neural activity associated with category-level information, such as reduced neural selectivity between categories of visual stimuli (e.g., scenes, objects, and faces). Here, I report a novel across-participant pattern similarity

SUBMITTER: Koen JD 

PROVIDER: S-EPMC8960356 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature