Eight Differential miRNAs in DN Identified by Microarray Analysis as Novel Biomarkers.

ABSTRACT:

Background

Diabetic nephropathy (DN) is the common cause of renal diseases such as end-stage renal disease (ESRD) and chronic kidney disease (CKD). Various diagnostic applications and treatment methods are used for clinical but remain some prognosis issues. To avoid morbidity and mortality related to DN, early detection of disease complications as well as targeted therapeutic strategies is essential. Considerable evidence indicates that non-coding RNA plays a vital role in the biological processes of various diseases, used as biomarkers and therapeutic targets. And the most known ncRNAs are the microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs).

Materials and methods

Our study aimed to identify potential prognostic ncRNAs involved in DN by bioinf

SUBMITTER: Tu C 

PROVIDER: S-EPMC8961165 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature