Short-term Outcomes of Corticosteroid Monotherapy in Multisystem Inflammatory Syndrome in Children.

ABSTRACT:

Importance

Optimal agents and duration of primary treatment for multisystem inflammatory syndrome in children (MIS-C) remain unclear.

Objective

To compare short-term patient outcomes based on initial treatment with corticosteroids, intravenous immunoglobulin (IVIG), or both.

Design, setting, and participants

This retrospective cohort study included patients in a tertiary-care pediatric hospital system who had MIS-C per the Centers for Disease Control and Prevention case definition during the period March 2020 to February 2021.

Exposures

Immunomodulatory therapy within the first 24 hours (patients in the intensive care unit [ICU]) or 48 hours (non-ICU patients): corticosteroids alone, IVIG alone, and IVIG plus corticosteroids.

Main outcomes and measures

P

SUBMITTER: Villacis-Nunez DS 

PROVIDER: S-EPMC8961405 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature