Grapevine DMR6-1 Is a Candidate Gene for Susceptibility to Downy Mildew.

ABSTRACT: Grapevine (Vitis vinifera) is a valuable crop in Europe for both economical and cultural reasons, but highly susceptible to Downy mildew (DM). The generation of resistant vines is of critical importance for a sustainable viticulture and can be achieved either by introgression of resistance genes in susceptible varieties or by mutation of Susceptibility (S) genes, e.g., by gene editing. This second approach offers several advantages: it maintains the genetic identity of cultivars otherwise disrupted by crossing and generally results in a broad-spectrum and durable resistance, but it is hindered by the poor knowledge about S genes in grapevines. Candidate S genes are Downy mildew Resistance 6 (DMR6) and DMR6-Like Oxygenases (DLOs), whose mutations confer re

SUBMITTER: Pirrello C 

PROVIDER: S-EPMC8961545 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature