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Risk factors for long-term survival in patients with ypN+ M0 rectal cancer after radical anterior resection.


ABSTRACT:

Background

Regional lymph node metastases are the main adverse prognostic factor in patients with rectal cancer without distant metastases. There are discrepancies, however, regarding additional risk factors in the group of ypN + M0 patients. The purpose of the study was to assess clinical and pathological factors affecting long-term oncological outcomes in the group of ypN + M0 patients after radical rectal anterior resection.

Methods

112 patients with ypN + M0 rectal cancer after neoadjuvant therapy and radical anterior resection were subject to a retrospective analysis. The effect of potential factors on survival was assessed with the use of Kaplan-Meier curves together with a log-rank test and multiple factor Cox proportional hazards model.

Results

In the multiple

SUBMITTER: Zeman M 

PROVIDER: S-EPMC8961971 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature