Immunotherapeutic Approaches for Glioblastoma Treatment.

ABSTRACT: Glioblastoma remains a challenging disease to treat, despite well-established standard-of-care treatments, with a median survival consistently of less than 2 years. In this review, we delineate the unique disease-specific challenges for immunotherapies, both brain-related and non-brain-related, which will need to be adequately overcome for the development of effective treatments. We also review current immunotherapy treatments, with a focus on clinical applications, and propose future directions for the field of GBM immunotherapy.

SUBMITTER: Yaghi NK 

PROVIDER: S-EPMC8962267 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature