Conducting density-sampled case-control studies using survey data with complex sampling designs: A simulation study.

ABSTRACT:

Purpose

Population-based surveys are possible sources from which to draw representative control data for case-control studies. However, these surveys involve complex sampling that could lead to biased estimates of measures of association if not properly accounted for in analyses. Approaches to incorporating complex-sampled controls in density-sampled case-control designs have not been examined.

Methods

We used a simulation study to evaluate the performance of different approaches to estimating incidence density ratios (IDR) from case-control studies with controls drawn from complex survey data using risk-set sampling. In simulated population data, we applied four survey sampling approaches, with varying survey sizes, and assessed the performance of four analysis methods for

SUBMITTER: Li CX 

PROVIDER: S-EPMC8962511 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature