Combined effects of air pollution and extreme heat events among ESKD patients within the Northeastern United States.

ABSTRACT:

Background

Increasing number of studies have linked air pollution exposure with renal function decline and disease. However, there is a lack of data on its impact among end-stage kidney disease (ESKD) patients and its potential modifying effect from extreme heat events (EHE).

Methods

Fresenius Kidney Care records from 28 selected northeastern US counties were used to pool daily all-cause mortality (ACM) and all-cause hospital admissions (ACHA) counts. County-level daily ambient PM_2.5 and ozone (O₃) were estimated using a high-resolution spatiotemporal coupled climate-air quality model and matched to ESKD patients based on ZIP codes of treatment sites. We used time-stratified case-crossover analyses to characterize acute exposures using individual and cu

SUBMITTER: Remigio RV 

PROVIDER: S-EPMC8962569 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature