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Health disparities experienced by Black and Hispanic Americans with multiple myeloma in the United States: a population-based study.


ABSTRACT: Hispanics and non-Hispanic (NH)-Blacks continue to face numerous health disparities related to multiple myeloma (MM). We aimed to analyze trends of MM-related hospitalizations and incidence of in-hospital mortality with a 10-year cross-sectional analysis of inpatient hospitalizations. The prevalence of MM-related hospitalizations was higher in NH-Blacks compared to NH-Whites (476.0 vs. 305.6 per 100,000 hospitalizations, p < .001). MM-related in-hospital mortality was higher in Hispanics compared to NH-Whites and NH-Blacks (6.2 vs. 5.3%, p < .001). Using average annual percent change (AAPC), we found a statistically significant decline of in-hospital mortality among all MM patients except NH-Blacks (AAPC: -2.2, 95% confidence interval (CI) -4.7, 0.4, p = .47), who had the highest inpatient mortality in recent years. Multivariate analysis showed that NH-Blacks received fewer transplants, more blood product transfusions, fewer palliative care consults, less inpatient chemotherapy, and utilized more intensive care. Disparities in MM care for NH-Blacks and Hispanics continue to persist despite recent advancements in MM therapy.

SUBMITTER: Al Hadidi S 

PROVIDER: S-EPMC8962656 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature

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Health disparities experienced by Black and Hispanic Americans with multiple myeloma in the United States: a population-based study.

Al Hadidi Samer S   Dongarwar Deepa D   Salihu Hamisu M HM   Kamble Rammurti T RT   Lulla Premal P   Hill LaQuisa C LC   Carrum George G   Ramos Carlos A CA   Heslop Helen E HE   Usmani Saad Z SZ  

Leukemia & lymphoma 20210718 13


Hispanics and non-Hispanic (NH)-Blacks continue to face numerous health disparities related to multiple myeloma (MM). We aimed to analyze trends of MM-related hospitalizations and incidence of in-hospital mortality with a 10-year cross-sectional analysis of inpatient hospitalizations. The prevalence of MM-related hospitalizations was higher in NH-Blacks compared to NH-Whites (476.0 vs. 305.6 per 100,000 hospitalizations, <i>p</i> < .001). MM-related in-hospital mortality was higher in Hispanics  ...[more]

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