Blood Nicotine Predicts the Behavioral Economic Abuse Liability of Reduced-Nicotine Cigarettes.

ABSTRACT:

Background

Cigarette smoking continues to be a major health concern and remains the leading preventable cause of death in the US. Recent efforts have been made to determine the potential health and policy benefits of reducing nicotine in combustible cigarettes. The degree to which changes in blood nicotine relate to measures of the abuse liability of reduced-nicotine cigarettes is unknown. The current study examined the relation between blood nicotine and behavioral economic demand measures of cigarettes differing in nicotine content.

Methods

Using a within-subject design, participants smoked a single cigarette during each experimental session. Cigarettes included the participant's usual-brand cigarette and SPECTRUM investigational cigarette differing in nicotine level (mg o

SUBMITTER: Kaplan BA 

PROVIDER: S-EPMC8962718 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature