Independent evaluation of the harvard automated processing pipeline for Electroencephalography 1.0 using multi-site EEG data from children with Fragile X Syndrome.

ABSTRACT:

Background

The Harvard Automatic Processing Pipeline for Electroencephalography (HAPPE) is a computerized EEG data processing pipeline designed for multiple site analysis of populations with neurodevelopmental disorders. This pipeline has been validated in-house by the developers but external testing using real-world datasets remains to be done.

New method

Resting and auditory event-related EEG data from 29 children ages 3-6 years with Fragile X Syndrome as well as simulated EEG data was used to evaluate HAPPE's noise reduction techniques, data standardization features, and data integration compared to traditional manualized processing.

Results

For the real EEG data, HAPPE pipeline showed greater trials retained, greater variance retained through independent component

SUBMITTER: Auger E 

PROVIDER: S-EPMC8962770 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature