A Systematic Review of the Progression of Cutaneous Lupus to Systemic Lupus Erythematosus.

ABSTRACT: Lupus erythematosus is an autoimmune disease that may manifest in a variety of organs and tissues including the skin, kidney, brain, heart and lung. Many patients present with cutaneous lupus, where disease is often limited to the skin, but are at risk for developing systemic lupus. The objective of our present study is to perform a systematic review of studies that investigated patient cohorts and populations for the occurrence of cutaneous lupus progressing to systemic lupus. Inclusion criteria required that studies present longitudinal data of patients with limited cutaneous lupus erythematosus who were followed for development of systemic lupus erythematosus. Studies were excluded if patients had concurrent diagnosis of SLE, or if they failed to present longitudinal data. Medline and E

SUBMITTER: Curtiss P 

PROVIDER: S-EPMC8963103 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature