Association of thyroid function with insulin resistance: data from two population-based studies.

ABSTRACT:

Objective

Thyroid dysfunction is associated with relevant disturbances in glucose metabolism. Moreover, thyroid function undergoes important changes with ageing. The objective of this study was to investigate the association of thyroid function with insulin resistance with particular consideration of possible age-related effect modifications.

Design

A sample of 4193 participants from two independent epidemiological studies, the Study of Health in Pomerania-TREND-0 and the Berlin Aging Study II, was included in this cross-sectional analysis.

Methods

Insulin resistance was estimated by homeostasis model of insulin resistance (HOMA-IR) and the insulin sensitivity index (ISI). Associations of thyroid biomarkers (thyroid-stimulating hormone, free thyroxine, and free triiod

SUBMITTER: Spira D 

PROVIDER: S-EPMC8963174 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature