The Temporal Relationship Between Local School Closure and Increased Incidence of Pediatric Diabetic Ketoacidosis.

ABSTRACT:

Importance

The incidence of pediatric diabetic ketoacidosis (DKA) increased early in the COVID-19 pandemic, but the relative contribution of behavioral changes and viral-related pathophysiology are unknown.

Objective

To evaluate the relationship between school closure date and onset of increased DKA to help clarify the etiology of the increased incidence.

Design

A multi-center, quality-controlled Pediatric Intensive Care Unit (PICU) database was used to identify the number of admissions to a participating PICU with DKA on each calendar day from 60 days before local school closure to 90 days after, and compared to baseline data from the same periods in 2018-2019. Interrupted time series and multiple linear regression analyses were used to identify admission rates that

SUBMITTER: McCluskey CK 

PROVIDER: S-EPMC8963207 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature