Core Size does not Affect Blinking Behavior of Dye-Doped Ag@SiO₂ Core-Shell Nanoparticles for Super-Resolution Microscopy.

ABSTRACT: Dye-doped nanoparticles have been investigated as bright, luminescent labels for super -resolution microscopy via localization methods. One key factor in super-resolution is the size of the luminescent label, which in some cases results in a frame shift between the label target and the label itself. Ag@SiO₂ core-shell nanoparticles, doped with organic fluorophores, have shown promise as super-resolution labels. One key aspect of these nanoparticles is that they blink under certain conditions, allowing super-resolution localization with a single excitation source in aqueous solution. In this work, we investigated the effects of both the Ag core and the silica (SiO₂) shell on the self-blinking properties of these nanoparticles. Both core size and shell thickness were ma

SUBMITTER: Thompson S 

PROVIDER: S-EPMC8963217 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature