Two CIDP Variants Patients With Anti-Caspr1 Antibodies in South China.

ABSTRACT:

Background and objectives

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is considered an immune-mediated heterogeneous disease that involves both cellular and humoral immunity. The advent of the new concept of node-paranodopathy in recent years has boosted the identification of more antibody-positive CIDP variants patients. Cases of Caspr1 autoantibodies are the least common. Here, we reported two patients with Caspr1 autoantibodies and summarized their clinical features and treatment responses.

Methods

Do statistical analyses on the clinical manifestations and laboratory examinations obtained from two patients identified in this study, and eight patients with anti-Caspr1 antibodies reported in previous research. And based on the developed scoring standard

SUBMITTER: Li C 

PROVIDER: S-EPMC8963365 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature