Arabidopsis Iron Superoxide Dismutase FSD1 Protects Against Methyl Viologen-Induced Oxidative Stress in a Copper-Dependent Manner.

ABSTRACT: Iron superoxide dismutase 1 (FSD1) was recently characterized as a plastidial, cytoplasmic, and nuclear enzyme with osmoprotective and antioxidant functions. However, the current knowledge on its role in oxidative stress tolerance is ambiguous. Here, we characterized the role of FSD1 in response to methyl viologen (MV)-induced oxidative stress in Arabidopsis thaliana. In accordance with the known regulation of FSD1 expression, abundance, and activity, the findings demonstrated that the antioxidant function of FSD1 depends on the availability of Cu²⁺ in growth media. Arabidopsis fsd1 mutants showed lower capacity to decompose superoxide at low Cu²⁺ concentrations in the medium. Prolonged exposure to MV led to reduced ascorbate levels and higher pro

SUBMITTER: Melicher P 

PROVIDER: S-EPMC8963501 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature