Impact of smoking status and chronic obstructive pulmonary disease on pulmonary complications post lung cancer surgery.

ABSTRACT:

Introduction

Smoking and chronic obstructive pulmonary disease (COPD) are associated with an increased risk of post-operative pulmonary complications (PPCs) following lung cancer resection. It remains unclear whether smoking cessation reduces this risk.

Methods

Retrospective review of a large, prospectively collected database of over 1000 consecutive resections for lung cancer in a quaternary lung cancer centre over a 23-year period.

Results

One thousand and thirteen patients underwent curative-intent lobectomy or pneumonectomy between 1995 and 2018. Three hundred and sixty-two patients (36%) were ex-smokers, 314 (31%) were current smokers and 111 (11%) were never smokers. A pre-operative diagnosis of COPD was present in 57% of current smokers, 57% of ex-smokers and 2

SUBMITTER: Jeganathan V 

PROVIDER: S-EPMC8963579 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature