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Sex differences and sex bias in human circadian and sleep physiology research.


ABSTRACT: Growing evidence shows that sex differences impact many facets of human biology. Here we review and discuss the impact of sex on human circadian and sleep physiology, and we uncover a data gap in the field investigating the non-visual effects of light in humans. A virtual workshop on the biomedical implications of sex differences in sleep and circadian physiology led to the following imperatives for future research: i) design research to be inclusive and accessible; ii) implement recruitment strategies that lead to a sex-balanced sample; iii) use data visualization to grasp the effect of sex; iv) implement statistical analyses that include sex as a factor and/or perform group analyses by sex, where possible; v) make participant-level data open and available to facilitate future meta-analyt

SUBMITTER: Spitschan M 

PROVIDER: S-EPMC8963875 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature