Distribution and Magnitude of Regional Volumetric Lung Strain and Its Modification by PEEP in Healthy Anesthetized and Mechanically Ventilated Dogs.

ABSTRACT: The present study describes the magnitude and spatial distribution of lung strain in healthy anesthetized, mechanically ventilated dogs with and without positive end-expiratory pressure (PEEP). Total lung strain (LS_TOTAL) has a dynamic (LS_DYNAMIC) and a static (LS_STATIC) component. Due to lung heterogeneity, global lung strain may not accurately represent regional total tissue lung strain (TS_TOTAL), which may also be described by a regional dynamic (TS_DYNAMIC) and static (TS_STATIC) component. Six healthy anesthetized beagles (12.4 ± 1.4 kg body weight) were placed in dorsal recumbency and ventilated with a tidal volume of 15 ml/kg, respiratory rate of 15 bpm, and zero end-expiratory pressure (ZEEP). Respiratory system mechan

SUBMITTER: Araos J 

PROVIDER: S-EPMC8964072 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature