Outcomes of Adult Liver Retransplantation: A Canadian National Database Analysis.

ABSTRACT:

Background

Liver retransplantation remains as the only treatment for graft failure. This investigation aims to assess the incidence, post-transplant outcomes, and risk factors in liver retransplantation recipients in Canada.

Materials and methods

The Canadian Organ Replacement Register was used to obtain and analyse data on all adult liver retransplant recipients, matched donors, transplant-specific variables, and post-transplant outcomes from January 2000 to December 2018.

Results

377 (6.5%) patients underwent liver retransplantation. Autoimmune liver disease and hepatitis C virus (HCV) were the most common underlying diagnoses. Graft failure was 7.9% and 12.5%, and overall survival was 77.1% and 65.6% at 1 year and 5 years, respectively. In contrast to recipients re

SUBMITTER: Yoon PD 

PROVIDER: S-EPMC8964213 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature