Diagnostic accuracy of SARS-CoV-2 saliva antigen testing in a real-life clinical setting.

ABSTRACT:

Background

SARS-CoV-2 antigen tests with saliva facilitate examination in settings that lack trained personnel. However, little is known about the diagnostic accuracy in real-life clinical settings. Therefore, we studied the diagnostic accuracy of a saliva antigen test in diagnosing SARS-CoV-2 infection in a primary/secondary care testing facility.

Methods

Individuals who presented at a COVID-19 testing facility affiliated with a Swiss university hospital were prospectively recruited (n=377). Saliva specimen was obtained, and the PCL Inc. COVID19 Gold antigen test was conducted in parallel with 2 real-time polymerase chain reaction (RT-PCR) assays from a nasopharyngeal swab.

Results

RT-PCR results were positive in 53 individuals, corresponding to a prevalence of 14.1%

SUBMITTER: Jegerlehner S 

PROVIDER: S-EPMC8964446 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature