Construction and validation of m⁶ A RNA methylation regulators associated prognostic model for gastrointestinal cancer.

ABSTRACT: N6-methyladenosine (m⁶ A) RNA methylation is correlated with carcinogenesis and dynamically possessed through the m⁶ A RNA methylation regulators. This paper aimed to explore 13 m⁶ A RNA methylation regulators' role in gastrointestinal cancer (GIC) and determine the risk model and prognosis value of m⁶ A RNA methylation regulators in GIC. We used several bioinformatics methods to identify the differential expression of m⁶ A RNA methylation regulators in GIC, constructed a prognostic model, and carried out functional enrichment analysis. Eleven of 13 m⁶ A RNA methylation regulators were differentially expressed in different clinicopathological characteristics of GIC, and m⁶ A RNA methylation regulators were nearly

SUBMITTER: Miao Y 

PROVIDER: S-EPMC8965361 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature