Observation of Clinicopathologic Features of Pituitary Adenoma With Neuronal Differentiation.

ABSTRACT:

Objective

To investigate the clinicopathologic features of pituitary adenoma with neuronal differentiation.

Methods

Four patients with mixed gangliocytoma-pituitary adenomas between January 2011 and January 2021 and 111 new-onset patients with adenomas between January 2019 and June 2021 who attended the First Affiliated Hospital of Fujian Medical University were included in the study. The histological and immunohistochemical findings were analyzed. Neuronal differentiation marker staining was performed on new-onset adenomas, and the related literature was reviewed.

Results

Altogether, more than 100 mixed gangliocytoma-pituitary adenoma cases have been reported in the literature until now, of which pituitary-specific POU-class homeodomain transcription 1 (PIT1) positiv

SUBMITTER: Zheng L 

PROVIDER: S-EPMC8965364 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature