Characterising older adults' risk of harm from blood-pressure lowering medications: a sub-analysis from the PRIME study.

ABSTRACT:

Aim

Cardiovascular disease (CVD) is common amongst frail older people. The evidence base for CVD commonly excludes older adults with multimorbidity or chronic conditions. Most cardiovascular drugs have the potential to lower blood pressure (BP) and therefore cause medication-related harm (MRH). We aimed to identify key clinical and sociodemographic characteristics associated with MRH in older people taking BP-lowering drugs for whatever indication they were prescribed.

Methods

The PRIME (prospective study to develop a model to stratify the risk of MRH in hospitalised elderly patients in the UK) study investigating the incidence and cost of MRH in older people across Southern England. Adults ≥65 years were recruited from five teaching hospitals at hospital discharge and follo

SUBMITTER: Hussain A 

PROVIDER: S-EPMC8966023 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature