C-Cl Oxidative Addition and C-C Reductive Elimination Reactions in the Context of the Rhodium-Promoted Direct Arylation.

ABSTRACT: A cycle of stoichiometric elemental reactions defining the direct arylation promoted by a redox-pair Rh(I)-Rh(III) is reported. Starting from the rhodium(I)-aryl complex RhPh{κ³-P,O,P-[xant(PⁱPr₂)₂]} (xant(PⁱPr₂)₂ = 9,9-dimethyl-4,5-bis(diisopropylphosphino)xanthene), the reactions include C-Cl oxidative addition of organic chlorides, halide abstraction from the resulting six-coordinate rhodium(III) derivatives, C-C reductive coupling between the initial aryl ligand and the added organic group, oxidative addition of a C-H bond of a new arene, and deprotonation of the generated hydride-rhodium(III)-aryl species to form a new rhodium(I)-aryl derivative. In this context, the kinetics of the oxidative additions of 2-c

SUBMITTER: de Las Heras LA 

PROVIDER: S-EPMC8966374 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature