Ti₃C₂T_x MXene-Coated Electrospun PCL Conduits for Enhancing Neurite Regeneration and Angiogenesis.

ABSTRACT: An electrical signal is the key basis of normal physiological function of the nerve, and the stimulation of the electric signal also plays a very special role in the repair process of nerve injury. Electric stimulation is shown to be effective in promoting axonal regeneration and myelination, thereby promoting nerve injury repair. At present, it is considered that electric conduction recovery is a key aspect of regeneration and repair of long nerve defects. Conductive neural scaffolds have attracted more and more attention due to their similar electrical properties and good biocompatibility with normal nerves. Herein, PCL and MXene-PCL nerve guidance conduits (NGCs) were prepared; their effect on nerve regeneration was evaluated in vitro and in vivo. The results show that the

SUBMITTER: Nan LP 

PROVIDER: S-EPMC8966647 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature