Total IgE in tears accurately reflects the severity and predicts the prognosis of seasonal allergic conjunctivitis.

ABSTRACT:

Background

Although immunoglobulin E (IgE) increases significantly in tears and serum during seasonal allergic conjunctivitis (SAC), it is unclear whether tear total IgE can reflect the severity and prognosis of SAC more accurately than serum total IgE. We aimed to investigate the usefulness of measuring the total IgE in tears to evaluate the severity and determine the treatment of SAC.

Methods

This prospective, nonrandomized study involved 55 patients with SAC and 10 age- and sex-matched healthy controls. Serum and tears were collected before and after treatment to analyze the total IgE. SAC patients received the same topical anti-allergy treatment and were followed-up every 2 weeks for 1 month. The relationship of tear and serum total IgE concentrations with pollen concent

SUBMITTER: Bao J 

PROVIDER: S-EPMC8967263 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature