Novel Zinc-Related Differentially Methylated Regions in Leukocytes of Women With and Without Obesity.

ABSTRACT:

Introduction

Nutriepigenetic markers are predictive responses associated with changes in "surrounding" environmental conditions of humans, which may influence metabolic diseases. Although rich in calories, Western diets could be linked with the deficiency of micronutrients, resulting in the downstream of epigenetic and metabolic effects and consequently in obesity. Zinc (Zn) is an essential nutrient associated with distinct biological roles in human health. Despite the importance of Zn in metabolic processes, little is known about the relationship between Zn and epigenetic. Thus, the present study aimed to identify the epigenetic variables associated with Zn daily ingestion (ZnDI) and serum Zinc (ZnS) levels in women with and without obesity.

Materials and methods

This is a

SUBMITTER: Noronha NY 

PROVIDER: S-EPMC8967318 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature