Ontology highlight
ABSTRACT:
SUBMITTER: Roellig D
PROVIDER: S-EPMC8967407 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Roellig Daniela D Theis Sophie S Proag Amsha A Allio Guillaume G Bénazéraf Bertrand B Gros Jérôme J Suzanne Magali M
Developmental cell 20220317 6
Apoptosis plays an important role in morphogenesis, and the notion that apoptotic cells can impact their surroundings came to light recently. However, how this applies to vertebrate morphogenesis remains unknown. Here, we use the formation of the neural tube to determine how apoptosis contributes to morphogenesis in vertebrates. Neural tube closure defects have been reported when apoptosis is impaired in vertebrates, although the cellular mechanisms involved are unknown. Using avian embryos, we ...[more]