Failed Breast Conservation Therapy Predicts Higher Frequency of Revision Surgery following Mastectomy with Reconstruction.

ABSTRACT:

Background

Breast conservation therapy remains the gold standard for women with localized breast cancer; however, some women may eventually undergo mastectomy with reconstruction. Little is understood regarding the risks of failed breast conservation therapy as they relate to postmastectomy reconstruction and whether this affects outcomes.

Methods

Patients undergoing breast reconstruction were extracted from the IBM MarketScan Commercial Database from 2007 to 2016. Frequency of lumpectomy and radiation therapy were determined per reconstructive patient. Outcomes included inpatient complications and frequency of revision procedures. Regression models were adjusted for age, obesity, timing of reconstruction, and Elixhauser Comorbidity Index.

Results

Six thousand two hun

SUBMITTER: Rochlin DH 

PROVIDER: S-EPMC8967810 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature