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Neuromuscular recovery from severe- and extreme-intensity exercise in men and women.

ABSTRACT: Maximal voluntary contraction force (MVC), potentiated twitch force (Q_pot), and voluntary activation (%VA) recover to baseline within 90 s following extreme-intensity exercise. However, methodological limitations mask important recovery kinetics. We hypothesized reductions in MVC, Q_pot, and %VA at task failure following extreme-intensity exercise would be less than following severe-intensity exercise, and Q_pot and MVC following extreme-intensity exercise would show significant recovery within 120 s but remain depressed following severe-intensity exercise. Twelve subjects (6 men) completed 2 severe-intensity (40, 50% MVC) and 2 extreme-intensity (70, 80% MVC) isometric knee-extension exercise bouts to task failure (T_lim). Neuromuscular function was measured at baseline, T_lim, and through 150 s of recovery. Each intensity significantly reduced MVC and Q_pot compared with baseline. MVC was greater at T_lim (p < 0.01) and at 150 s of recovery (p = 0.004) following exercise at 80% MVC compared with severe-intensity exercise. Partial recovery of MVC and Q_pot were detected within 150 s following T_lim for each exercise intensity; Q_pot recovered to baseline values within 150 s of recovery following exercise at 80% MVC. No differences in %VA were detected pre- to post-exercise or across recovery for any intensity. Although further analysis showed sex-specific differences in MVC and Q_pot, future studies should closely examine sex-dependent responses to extreme-intensity exercise. It is clear, however, that these data reinforce that mechanisms limiting exercise tolerance during extreme-intensity exercise recover quickly. Novelty: Severe- and extreme-intensity exercise cause independent responses in fatigue accumulation and the subsequent recovery time courses. Recovery of MVC and Q_pot occurs much faster following extreme-intensity exercise in both men and women.

SUBMITTER: Alexander AM

PROVIDER: S-EPMC8969115 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature

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Neuromuscular recovery from severe- and extreme-intensity exercise in men and women.

Alexander Andrew M AM Hammer Shane M SM Didier Kaylin D KD Huckaby Lillie M LM Barstow Thomas J TJ

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20220112 4

Maximal voluntary contraction force (MVC), potentiated twitch force (Qpot), and voluntary activation (%VA) recover to baseline within 90 s following extreme-intensity exercise. However, methodological limitations mask important recovery kinetics. We hypothesized reductions in MVC, Qpot, and %VA at task failure following extreme-intensity exercise would be less than following severe-intensity exercise, and Qpot and MVC following extreme-intensity exercise would sh ...[more]

PMID: 35020495

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Project description:BackgroundShort-term exercise training programs that consist of moderate intensity endurance training or high intensity interval training have become popular choices for healthy lifestyle modifications, with as little as two weeks of training being shown to improve cardiorespiratory fitness and whole-body glucose metabolism. An emerging concept in exercise biology is that exercise stimulates the release of cytokines and other factors into the blood that contribute to the beneficial effects of exercise on metabolism, but whether these factors behave similarly in response to moderate and high intensity short term training is not known. Here, we determined the effects of two short-term exercise training programs on the concentrations of select secreted cytokines and Klotho, a protein involved in anti-aging.MethodsHealthy, sedentary men (n = 22) were randomized to moderate intensity training (MIT) or sprint intensity training (SIT) treatment groups. SIT consisted of 6 sessions over 2 weeks of 6 × 30 s all out cycle ergometer sprints with 4 min of recovery between sprints. MIT consisted of 6 sessions over 2 weeks of cycle ergometer exercise at 60% VO2peak, gradually increasing in duration from 40 to 60 min. Blood was taken before the intervention and 48 h after the last training session, and glucose uptake was measured using [18F]FDG-PET/CT scanning. Cytokines were measured by multiplex and Klotho concentrations by ELISA.ResultsBoth training protocols similarly increased VO2peak and decreased fat percentage and visceral fat (P < 0.05). MIT and SIT training programs both reduced the concentrations of IL-6, Hepatocyte Growth Factor (HGF) and Leptin. Interestingly, MIT, but not SIT increased monocyte chemoattractant protein-1 (MCP-1) concentrations, an exercise-induced cytokine, as well as Klotho concentrations.ConclusionShort-term exercise training at markedly different intensities similarly improves cardiovascular fitness but results in intensity-specific changes in cytokine responses to exercise.

Dataset Information

Neuromuscular recovery from severe- and extreme-intensity exercise in men and women.

Publications

Neuromuscular recovery from severe- and extreme-intensity exercise in men and women.

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