Evaluation of the diagnostic performance and the utility of Helicobacter pylori stool antigen lateral immunochromatography assay.

ABSTRACT:

Background

Helicobacter pylori causes the most common human gastric infection. H. pylori Stool Antigen Lateral Flow Immunochromatography assay (HpSA-LFIA) is considered one of the most cost-effective and rapid non-invasive assays (active tests). Evaluating HpSA-LFIA is of crucial for ensuring accuracy and utility assurance. This study aimed to evaluate the polyclonal antibody-based HpSA-LFIA in comparison to a monoclonal antibody-based ELISA kit.

Methodology

Stool samples were collected from 200 gastric patients for HpSA-LFIA and semiquantitative HpSA-ELISA tests. A statistical analysis of the diagnostic performance was performed using MedCalc software. Chi-square tests were performed to determine the effects of gender and age.

Results and conclusion

The

SUBMITTER: Abdelmalek S 

PROVIDER: S-EPMC8969150 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature