Exploration of Hanshi Zufei prescription for treatment of COVID-19 based on network pharmacology.

ABSTRACT:

Objective

Network pharmacology combines drug and disease targets with biological information networks based on the integrity and systematicness of the interactions between drugs and disease targets. This study aims to explore the molecular basis of Hanshi Zufei formula for treatment of COVID-19 based on network pharmacology and molecular docking techniques.

Methods

Using TCMSP, the chemical constituents and molecular targets of Atractylodis Rhizoma, Citri Reticulatae Pericarpium, Magnoliae Officinalis Cortex, Pogostemonis Herba, Tsaoko Fructus, Ephedrae Herba, Notopterygii Rhizoma et Radix, Zingiberis Rhizoma Recens, and Arecae Semen were investigated. The predicted targets of novel coronavirus were screen

SUBMITTER: Li X 

PROVIDER: S-EPMC8969322 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature