Longitudinal relationship of baseline functional brain networks with intentional weight loss in older adults.

ABSTRACT:

Objective

The goal of this study was to determine whether the degree of weight loss after 6 months of a behavior-based intervention is related to baseline connectivity within two functional networks (FNs) of interest, FN1 and FN2, in a group of older adults with obesity.

Methods

Baseline functional magnetic resonance imaging data were collected following an overnight fast in 71 older adults with obesity involved in a weight-loss intervention. Functional brain networks in a resting state and during a food-cue task were analyzed using a mixed-regression framework to examine the relationships between baseline networks and 6-month change in weight.

Results

During the resting condition, the relationship of baseline brain functional connectivity and network clustering in FN

SUBMITTER: Burdette JH 

PROVIDER: S-EPMC8969753 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature