Untreated head and neck cancer: Natural history and associated factors.

ABSTRACT:

Background

This study aims to provide modern estimates of survival for untreated head and neck cancer (HNC) and to identify patient- and tumor-specific factors associated with not receiving definitive treatment.

Methods

Adults with mucosal HNC were identified from the Surveillance, Epidemiology, and End Results (SEER) database. Median overall survival of untreated patients was calculated and stratified by site and stage. Cause-specific survival and factors associated with no treatment were investigated with advanced statistics.

Results

The study cohort included 6477 patients who received no treatment. Overall, untreated patients had a median survival of 12 months, with significant variability by site and stage. Multivariable analysis identified advanced age, black rac

SUBMITTER: Zolkind P 

PROVIDER: S-EPMC8970342 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature