Preadmission use of antidiabetic medications and mortality among patients with COVID-19 having type 2 diabetes: A meta-analysis.

ABSTRACT:

Background

Diabetes is an independent predictor of poor outcomes in patients with COVID-19. We compared the effects of the preadmission use of antidiabetic medications on the in-hospital mortality of patients with COVID-19 having type 2 diabetes.

Methods

A systematic search of PubMed, EMBASE, Scopus and Web of Science databases was performed to include studies (except case reports and review articles) published until November 30, 2021. We excluded papers regarding in-hospital use of antidiabetic medications. We used a random-effects meta-analysis to calculate the pooled OR (95% CI) and performed a sensitivity analysis to confirm the robustness of the meta-analyses.

Main findings

We included 61 studies (3,061,584 individuals), which were rated as having low risk of bia

SUBMITTER: Nguyen NN 

PROVIDER: S-EPMC8970613 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature